PRODUCT PIPELINE

Our Innovative siRNA Drugs

Target and Degrade Virus’s DNA
Universal targeting viral mutation & escape
Gene delivery technology
IG-001

Coronavirus Disease

(SARS-CoV-2)

IG-002
Flu
Listed
Phase III
Phase II
Phase I
Preclinical
Discovery

IG-001

siRNA drug for Covid treatment

Challenges

Economic Losses:

The COVID-19 pandemic has caused significant economic losses exceeding 20 trillion USD globally.

Vaccine Hesitancy:

Despite the introduction of mRNA vaccines, vaccine hesitancy among the public continues to persist.

Evolving virus:

The threat posed by both the original and new variants of the virus continuously creates health concerns.

Opportunities

siRNA Innovation:

The FDA in the United States has approved several drugs for treating COVID-19, including antiviral medications, immune modulators, and renal replacement therapies.

IG-001, developed by Intelligene, is an siRNA drug that uses gene coding to combat the virus. We anticipate that IG-001 will provide precise targeted therapy for both known and potentially unknown variants.

IG-002

siRNA-based drug for universal flu treatment

Challenges

High Incidence and Severity:

Flu (Influenza) continues to be a significant public health challenge with an estimated 1 billion cases worldwide each year, including 3 to 5 million severe cases and hundreds of thousands of related respiratory deaths.

Emerging Pandemic Risk:

Recent lab tests with bird flu strains show that these viruses keep changing and can be a big health risk when they spread from animals to people. This warns us about possible big disease outbreaks or pandemics.

Opportunities

Advanced Drug Development:

IG-002 offers an opportunity for advanced gene therapy by targeting a conserved region in the virus' evolution, potentially addressing various flu strains.

Comprehensive and Precise Solution:

We expect IG-002 offer a more comprehensive and accurate nucleic acid therapeutic drugs with RNAi technology targeting specific genes and regions.

Remark

“We found that the administration and access to vaccine were some of the major concerns. While most of the information was received from the internet, they were not directly obtained from the health organization. Misinformation may cause negative emotions. In some cases, conspiracy spreading in social media may cause substantial amount of fear.” – “Topics and Sentiments of Public Concerns Regarding COVID-19 Vaccines: Social Media Trend Analysis”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534488/

“the COVID-19 pandemic remains a high priority for the Center for Drug Evaluation and Research (CDER). CDER will remain engaged with numerous activities to protect and promote public health.”

https://www.fda.gov/drugs/emergency-preparedness-drugs/coronavirus-covid-19-drugs

“Influenza is a serious global health threat that impacts all countries: every year, up to 650 000 people die of respiratory diseases related to seasonal influenza.” –WHO website “Influenza is on the rise”

https://www.who.int/news/item/01-10-2021-influenza-is-on-the-rise-how-do-i-prevent-it

British Daily Mail “Bird flu strain in China has 'pandemic potential', scientists warn”

https://www.msn.com/en-au/health/health-newsbird-flu-strain-in-china-has-pandemic-potential-scientists-warn/